Multiple full-length CFTR structures provide insight into the conformational changes associated with channel gating and the binding sites associated with the Vertex and Galapagos potentiator molecules.  

This website was designed as part of the CFTR 3D Structure Consortium with the goal of  disseminating structural biology data, tools, and reagents to the CF community.  The website is being maintained with support from the CFF with the goal of faciltiating CFTR structural biology and disseminating information about this research to the CF community.  


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© 2019 CFTR 3D-Structure Consortium; Updated October 7, 2019